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The effectiveness and safety of beginning insulin aspart together with basal insulin in people with type 2 diabetes in non-Western nations: Results from the A1chieve observational study

Philip D. Home, Zafar A. Latif, Guillermo González-Gálvez, Vinay Prusty and Zanariah Hussein

Diabetes Research and Clinical Practice, 3, 101, pages 326 - 332

Received 3 January 2013, Revised 15 May 2013, Accepted 6 June 2013, Published online Oct-2013

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2. Participants

The aim was to examine those who added insulin aspart to existing basal insulin; those who switched from biphasic insulin to basal plus insulin aspart; those who switched from NPH insulin plus human soluble insulin to basal plus insulin aspart; and those who were insulin-naïve and started a basal plus insulin aspart regimen. In this sub-analysis, 1594 participants were insulin-naïve prior to the A1chieve study, 519 were using basal insulin alone (± oral glucose-lowering drugs [OGLDs]), 947 premix insulin, 746 basal insulin plus a meal-time human insulin (of whom 586 were using NPH insulin plus meal-time human insulin), and 301 were using other insulin regimens.

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