A1chieve study reports

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Global

You are currently viewing the overall study results for Global.
Country or region: Global
Treatment: All
Pre-treatment 1: Insulin naïve
Pre-treatment 2: Insulin users

Safety data

Click here to add this chart to your selection. Click here to remove this chart from your selection. Adverse Events N (%) E (All)

Parameters Insulin naïve Insulin users
N 44872 21854
ADR 42 ( 0.1) 42 43 ( 0.2) 43
SADR 10 ( 0.0) 10 26 ( 0.1) 26
SAE 94 ( 0.2) 94 120 ( 0.5) 120

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Baseline value
1.1 7.3
0.3 2.2
0.1 0.8
Final value
1.2 2.5
0.3 0.6
0.0 0.0
N
38810 18581
38810 18581
38810 18581

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Baseline value
72.1 75.7
Final value
72.2 75.7
N
33716 16343
P*
<0.001 0.081

Click here to add this chart to your selection. Click here to remove this chart from your selection. Insulin Dose (All)

N
0 21847
44804 21794
38690 18548

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N
5461 4631
12752 8922
14748 11570
14073 15727

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N
3998 3160
8197 5926
9882 7853
6980 7192

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Parameters Insulin naïve (baseline) Insulin naïve (week 24) Insulin naïve (change from baseline) Insulin naïve (number of patients) Insulin naïve (p-value)
LDL-C (mmol/L) 3.2 2.7 -0.4 10304 <0.001
HDL-C (mmol/L) 1.2 1.2 0.1 10189 <0.001
Triglycerides (mmol/L) 2.1 1.7 -0.4 11672 <0.001
SBP (mmHg) 134.0 127.3 -6.6 29595 <0.001

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Parameters Insulin users (baseline) Insulin users (week 24) Insulin users (change from baseline) Insulin users (number of patients) Insulin users (p-value)
LDL-C (mmol/L) 3.1 2.8 -0.3 7190 <0.001
HDL-C (mmol/L) 1.1 1.2 0.0 7117 <0.001
Triglycerides (mmol/L) 2.0 1.8 -0.3 8184 <0.001
SBP (mmHg) 134.7 129.0 -5.7 15690 <0.001

* P is only available for N ≥ 100